The Gilbert group – University of Copenhagen

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GeoGenetics > Research groups > The Gilbert group

The Gilbert Group

In 2010 a ‘Sapere Aude' award enabled the initiation of a large research project that aimed to use state of the art genetic and protein sequencing techniques to uncover in detail the biomolecular changes undergone by maize during its domestication. The award from the Ministry of Science, Technology and Innovation was received by Associate Professor Tom Gilbert, Centre for GeoGenetics, Natural History Museum of Denmark. Read more.

The interests of our group are wide, although all have an underlying thread of evolutionary biology, anthropology and, occasionally, archaeology. To achieve this, we use both ancient and modern biomolecular data (DNA, RNA and proteins), generated using conventional and high-throughput analysis platforms. Much of our research is in close collaboration with the research groups of Eske Willerslev and Ludovic Orlando. Read more.

Furthermore Professor Gilbert is Project Manager & Supervisor on the project 'Exploring the History, Archaeology and New Genetics of the Transatlantic Slave Trade (EUROTAST).

Selected papers from the group

Mitogenomics
* Foote AD et al. (2010) Positive selection on the killer whale mitogenome. Biology Letters
* Morin PA et al. (2010) Complete mitochondrial genome phylogeographic analysis of killer whales (Orcinus orca) indicates multiple species. Genome Research 7:908-916

Ancient Biomolecules
* Campos P et al. (2010) Ancient DNA sequences point to a large loss of mitochondrial genetic diversity in the saiga antelope (Saiga tatarica) since the Pleistocene. Molecular Ecology 19:4863-4875
* Campos P et al. (2010) Ancient DNA analyses exclude humans as the driving force behind late Pleistocene musk ox (Ovibos moschatus) population dynamics. Proc Natl Acad Sci USA 105:8327-8332
* Rasmussen M, et al. (2010) Ancient human genome sequence of an extinct Palaeo-Eskimo. Nature 463: 757-762
* Gilbert MTP et al. SC (2008). Intraspecific Phylogenetic Analysis of Siberian Woolly Mammoths Using Complete Mitochondrial Genomes. Proc Natl Acad Sci USA 105:8327-8332
* Gilbert MTP et al. (2008) Paleo-Eskimo MtDNA genome reveals matrilineal discontinuity in Greenland. Science 320:1787-1789
* Gilbert MTP et al. (2008) DNA from Pre-Clovis human coprolites in Oregon, North America. Science 329:786-789
* Wilson AS et al. (2007) Inca child sacrifice: isotopic and DNA evidence for ritual sequences. Proc Natl Acad Sci USA 104:16456-16461

Novel Sources of Nucleic Acids
* Bærholm Schnell I et al. (2010) Characterisation of insect and plant origins using DNA extracted from small volumes of bee honey. Arthropod-Plant Interactions 4:107-116
* Gilbert MTP et al. (2007) Whole-Genome shotgun sequencing of mitochondria from ancient hair shafts. Science 317:1927-1930
* Gilbert MTP et al. (2007) The isolation of nucleic acids from fixed, paraffin embedded tissues - which methods are useful when? PLoS ONE 6:e537

Viral Evolution
* Katzourakis A et al. (2009) The macroevolution of complex retroviruses. Science 325:1512
* Worobey M et al. (2008) Direct evidence of extensive diversity of HIV-1 in Kinshasa by 1960. Nature 455:61-664
* Gilbert MTP et al. (2007) Emergence of HIV/AIDS in the Americas and Beyond. Proc Natl Acad Sci USA 104:18566-18570

Phylogenetics and Molecular Ecology
* Foote A et al. (2009). Ecological, morphological and genetic divergence of sympatric North Atlantic killer whale populations. Molecular Ecology 18:5207-5217
* Willerslev E et al. (2009) Analysis of complete mitochondrial genomes from extinct and extant rhinoceroses reveals lack of phylogenetic resolution. BMC Evolutionary Biology 9:95